The length of treatment for colorectal cancer (CRC) patients in the adjuvant setting is a controversial topic. Recent studies have compared the outcomes for patients receiving adjuvant therapy with FOLFOX or CAPOX for 3 or for 6 months. What should be the recommended length of treatment for CRC patients in the adjuvant setting? Do recent data support a 3-month or 6-month duration? The following e-learning course includes expert opinions on the latest answers to these important questions.